10º Foro de Inmunologia Traslacional en Inmmunoterapia del cáncer

15 10º FORO DE Inmunología Traslacional e INMUNOTERAPIA DEL CÁNCER 15:30-15:37 CO-01. CAR-T cells secreting T cell engagers show superior control of leukemia progression than tandem CAR-T cells Javier Arroyo-Ródenas1; Laura Díez-Alonso1; Aida Falgas2; Alba MartínezMoreno2; Francisco J. Gil-Etayo1; Óscar Aguilar-Sopeña3; Miriam VelascoSidro1; Clara Bravo-Martín3; Ángel Ramírez-Fernández1; Belén Blanco1; Pedro Roda-Navarro3; Clara Bueno2; Pablo Menéndez2; Luis Álvarez-Vallina1 1Cancer Immunotherapy Unit (UNICA), Department of Immunology, Hospital Universitario 12 de Octubre, Madrid, Spain; Immuno-Oncology and Immunotherapy Group, Instituto de Investigación Sanitaria Hospital 12 de Octubre (imas12), H12O-CNIO, Madrid, Spain. 2Josep Carreras Leukaemia Research Institute, Barcelona, Spain; Red Española de Terapias Avanzadas (TERAV), Instituto de Salud Carlos III, Madrid, Spain. 3Department of Immunology, Ophthalmology and ENT, School of Medicine, Universidad Complutense de Madrid, Madrid, Spain; Lymphocyte Immunobiology Group, Instituto de Investigación Sanitaria 12 de Octubre (imas12), Madrid, Spain 15:37-15:44 CO-02. Targeting tumour-promoting inflammation in breast cancer by Oncostatin M (OSM) cytokine blockade: implications in immune suppression Maria Muñoz Caffarel; Peio Azcoaga; Andrea Abaurrea; Sara Manzano; Paloma Petit de Prado; Irati Garmendia; Ander Urruticoechea IIS Biogipuzkoa, Hospital Universitario Donostia, San Sebastián, Guipuzkoa 15:44-15:51 CO-03. Overcoming tumor heterogeneity with dual-targeted STAb-T cells secreting two T cell engagers for the treatment of multiple myeloma Miriam Velasco-Sidro1,2,3, Javier Arroyo-Ródenas1,2,3, Laura Díez-Alonso1,2,3, Ángel Ramírez-Fernández1,2,3,§, Luis Álvarez-Vallina1,2,3 1Cancer Immunotherapy Unit (UNICA), Department of Immunology, Hospital Universitario12 de Octubre, 28041 Madrid, Spain. 2Immuno-Oncology and Immunotherapy Group, Instituto de Investigación Sanitaria 12 de Octubre (imas12), 28041 Madrid, Spain. 3H12O-CNIO Cancer Immunotherapy Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain. §Current address: Center for Advanced Cellular Therapies. Perelman Center for Advanced Medicine, University of Pennsylvania, Philadelphia, PA, United States. 15:51-15:58 CO-04. Next-generation multispecific CAR-T cells: towards a new structured approach for adoptive cell therapies Alejandro Segura-Tudela; Laura Rubio-Pérez; Ángel Ramírez-Fernández; María Lasa-Lázaro; Luis Álvarez-Vallina Hospital Universitario 12 de Octubre, Madrid, Spain 15:58-16:00 Discussion - Discusión

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